Overview
Cylert is the brand name for Pemoline — a CNS (central nervous system) stimulant. This medication is usually used in children, and it is rarely used after puberty. Cylert is available in regular or chewable tablets.

Cylert usually begins to work within a few days, though it's full effects may not be felt for 3 to 4 weeks.

Why is this drug prescribed?
Cylert is used to treat attention-deficit hyperactivity disorder (ADHD).

Warnings and Precautions
This drug is not recommended for children under 6 years old.

Cylert can be very habit-forming, and cause psychological and physical dependence. However, this is rare in children, and more caution is required for adult patients. Suddenly discontinuing this medication may cause withdrawal symptoms.

For Pregnant or Nursing Mothers: Cylert has caused problems in animal pregnancy. It is not known whether this drug passes into breast milk. Cylert is not recommended for pregnant or nursing mothers.

Contraindications
Cylert should Not be used for people with an allergy to this medication.

Precautions
Cylert may be used with caution in people with the following conditions:

1. epilepsy or a family history of seizures
2. a history of Tourette's syndrome
3. liver, kidney, or heart disease
4. psychotic behavior (especially in children)
5. emotional instability or a history or drug dependence — increases risk of addiction and misuse of this drug
6. severe mental illness — Cylert may make the condition worse

Adverse Reactions
Cylert may cause the following reactions:

1. difficulty sleeping (insomnia)
2. loss of appetite
3. agitation
4. irritability
5. weight loss
6. abdominal pain
7. headache
8. nausea
9. drowsiness
10. dizziness
11. dry mouth
12. mood changes / depression
13. lack of coordination
14. tics/unusual movements
15. skin rash
16. liver irritation/toxicity
17. yellow eyes / skin
18. chest pain
19. hallucinations
20. increased heart rate
21. tics
22. Tourette's syndrome

Interactions with Drugs and Other Substances
Drugs or substances that may interact with Cylert include:

1. MAO Inhibitors (within 14 days) — combination with Cylert may lead to sudden high blood pressure or fever, irregular heartbeat, or seizures
2. heterocyclic antidepressants
3. antiepileptic drugs (such as Tegretol)
4. other CNS stimulants such as Ritalin, amantadine (Symmetrel), amphetamines, appetite suppressants (diet pills), caffeine (NoDoz), chlophedianol (Ulone), cocaine, asthma medication, cold medicine, sinus medicine, antihistamines (including nose drops or sprays), nabilone (Cesamet) — these medications increase the stimulant effect of Cylert, and may lead to severe nervousness, irritability, trouble in sleeping, irregular heartbeat, or seizures
5. anticonvulsants — Cylert can reduce the effectiveness of these medications

Sources

http://www.psyweb.com/Drughtm/cylert.html

http://www.health-center.com/db/PageReq?SessionID=1299&TopicID=339&PageID=1367&Action=view

http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=use0342.htm&title=Cylert&cid=HT

http://www.rxmed.com/monographs/cylert.html