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The Drugs
The Medications Rx
 

Fluvoxamine Maleate
Brand Name: Luvox

Overview
Luvox is the brand name for Fluvoxamine, an antidepressant and antiobsessional drug. Luvox is a Serotonin Reuptake Inhibitor (SSRI). It is often prescribed for Obsessive Compulsive Disorder (OCD). This drug is used to relieve anxiety and unpleasant thoughts that cause a person to repeat certain tasks.

Why is this drug prescribed?
Luvox is used primarily to treat Obsessive Compulsive Disorder (OCD.) The obsessions or compulsions must cause marked distress, are time-consuming, or significantly interfere with social or occupational functioning.

Luvox is also used to treat:

  1. depression
  2. panic disorder
  3. eating disorders
  4. chronic tension headaches

Warnings and Precautions
Luvox has been tested in children with obsessive-compulsive disorder (although there is less dosage information available for children under eight years old) and it has not been shown to cause different side effects or problems than it does in adults. Because Luvox can cause decreased appetite, children taking Luvox long-term should have their growth and body weight measured regularly.

Luvox does not cause dependency, however withdrawal symptoms may occur if a patient stops taking Luvox suddenly. To avoid withdrawal, the dosage should be tapered gradually.

Luvox may interfere with judgment, thinking, or motor skills. Patients should not drive or operate heavy machinery until the effects of Luvox on that patient are known.

For Nursing Mothers: Luvox is secreted in human breast milk. The decision of whether to discontinue nursing or to discontinue the drug should take into account the potential for serious adverse effects to the nursing infant as well as the potential benefits of Luvox to the mother.

Contraindications
In patients with liver disease or dysfunction, Luvox should be slowly titrated in patients during the initiation of treatment. The dosage may need to be lowered in patients with liver or kidney disease.

Adverse Reactions
Luvox may cause the following reactions:

  1. dry mouth
  2. constipation
  3. decreased appetite
  4. nausea
  5. insomnia
  6. drowsiness
  7. dizziness
  8. headache
  9. agitation
  10. sleep disorders
  11. diarrhea
  12. weakness/loss of strength
  13. hypomania
  14. liver toxicity
  15. nervousness
  16. sexual problems (delayed or absent orgasm)

Interactions with Drugs and Other Substances
Drugs or substances that may interact with Luvox are:

  1. MAO Inhibitors when taking Luvox - serious, possibly fatal, interactions can occur when taking these medications together.
  2. Seldane (terfenadine) or Hismanal (astemizole) serious heart arrhythmias that may occur when these medications are taken with Luvox.
  3. Elavil (amitriptyline), benzodiazepines, Tegretol (carbamazepine), Tagamet (cimetidine), Anafranil (clomipramine), Clozaril (clozapine), Tofranil (imipramine), Lithium, maprotiline, Dilantin (phenytoin), and theophylline may lead to drug toxicity when taken with Luvox.
  4. Ultram (tramadol) can add to the risk of seizures.
  5. Tryptophan may cause severe vomiting.
  6. Coumadin (warfarin) may lead to bleeding.
  7. Marijuana smoking may add to the drowsiness effect of Luvox.

Sources

http://www.health-center.com/db/PageReq?SessionID=3280&TopicID=424&PageID=2242&Action=view

http://www.rxlist.com/scripts/patient/piumore.pl?mononum=854&dc_category=&order=0&type=&item=

http://www.fairlite.com/ocd/medications/luvox.shtml

http://www.psyweb.com/Drughtm/luvox.html

 
   
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