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The Drugs
The Medications Rx
 

Ethosuximide
Brand Name: Zarontin

Overview
Zarontin is a brand name for ethosuximide, an anticonvulsant used to treat epilepsy. It is a succinimide anticonvulsant related to the drug methsuximide.

Why is this drug prescribed?
Zarontin is used to treat epileptic seizures, especially absence (petit mal) seizures.

Warnings and Precautions
Children taking Zarontin should be carefully monitored. Parents and teachers should keep track of the child’s moods, behavior, attention span, hand-eye coordination, and ability to solve problems and perform tasks requiring thought. This information can help the doctor determine the proper maintenance dosage.

Zarontin may cause drowsiness. Patients should not drive or perform tasks requiring mental alertness until Zarontin’s effects are known to be safe for these activities.

Abruptly discontinuing Zarontin may cause a return or increase in seizures, especially when Zarontin has been taken for a long time. Dosage should be gradually tapered when it is discontinued.

Zarontin causes the eyes to become more sensitive to light. Patients should wear sunglasses while in bright light.

Zarontin, when used alone to treat patients with mixed types of epilepsy, can increase the incidence of generalized tonic-clonic seizures in some patients.

Regular liver, kidney, and blood tests are recommended for all patients taking Zarontin.

For Pregnant or Nursing Mothers: While most pregnant women taking epilepsy medication deliver normal babies, epilepsy medications taken during pregnancy are associated with an increased risk of birth defects. Zarontin passes into breast milk, and breast-feeding while taking Zarontin is not recommended.

Contraindications
Zarontin should Not be used for people with an allergy or sensitivity to Zarontin or other succinimides.

Precautions
Zarontin may be used with caution in people with the following conditions:

  1. Liver or kidney disease – Zarontin may make these conditions worse
  2. Blood disorder

Adverse Reactions
Zarontin may cause the following reactions:

  1. Upset stomach (can be reduced by taking Zarontin with food and plenty of water)
  2. Muscle pain
  3. Rash and itching
  4. Sore throat and fever
  5. Drowsiness
  6. Upset stomach
  7. Vomiting
  8. Constipation
  9. Diarrhea
  10. Stomach pain
  11. Loss of taste and appetite
  12. Weight loss
  13. Irritability
  14. Mental confusion
  15. Depression
  16. Insomnia
  17. Nervousness
  18. Headache

Interactions with Drugs and Other Substances
Drugs or substances that may interact with Zarontin include:

  1. Vibramycin (doxycycline)
  2. Isoniazid (INH)
  3. Cold or allergy medications
  4. Anti-depressants
  5. Oral contraceptives may not function correctly while taking Zarontin. A secondary or alternate method of birth control should be used.
  6. Alcohol – may increase the side effect of drowsiness
  7. Any other seizure medication – combinations are possible and frequently used, but should be carefully monitored for interactions.

Sources

http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682327.html

http://www.rxmed.com

http://www.healthtouch.com

http://www.mentalhealth.com

 
   
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