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The Drugs
The Medications Rx
 

Venlafaxine hydrochloride
Brand Name: Effexor

Overview
Effexor is a bicyclic antidepressant that is not chemically related to tricyclic antidepressants or to other commonly prescribed antidepressants. This drug is often used to treat depression which has not responded to other medications.

Why is this drug prescribed?
Effexor is used to treat major depressive disorder with melancholia that has not responded to other medications.

This drug is also occasionally used to treat OCD (obsessive-compulsive disorder) or Fibromyalgia (FMS).

Warnings and Precautions
Effexor is not known to be addictive, but withdrawal symptoms may be present when this drug is discontinued in patients who have taken it for a long time. Dosage should be gradually tapered to avoid withdrawal.

It is recommended that patients receiving Effexor regularly monitor blood pressure. Patients whose blood pressure increases while taking Effexor should discontinue or reduce the dosage.

Effexor may cause drowsiness, dizziness or blurred vision. Patients using Effexor should not drive, use machinery, until the effects of Effexor on that patient are known. Alcohol may increase dizziness or drowsiness.

For Nursing Mothers: It is not known whether Effexor is excreted in breast milk, but as with all drugs, caution should be used.

The safety and effectiveness in children and adolescents under 18 are not known — Effexor should not be used in children for either OCD or depression.

Contraindications
Dosage of Effexor will probably have to be altered in patients with high blood pressure, heart, liver, or kidney disease.

Adverse Reactions
Effexor may cause the following reactions:

  1. headache
  2. weight loss
  3. nausea
  4. dizziness
  5. sleepiness
  6. abnormal ejaculation
  7. anorexia
  8. constipation
  9. nervousness or anxiety
  10. excessive sweating
  11. dry mouth
  12. blurry vision
  13. diarrhea
  14. insomnia
  15. hypomania
  16. increased blood pressure
  17. seizures
  18. weakness
  19. difficulty breathing

Interactions with Drugs and Other Substances
Drugs or substances that may interact with Effexor are:

  1. alcohol
  2. cimetidine
  3. medications for weight control or appetite
  4. MAO inhibitors-phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®) - serious, even fatal, interactions can occur when these medications are taken with Effexor.
  5. other medicines for mental depression, mania, or anxiety
  6. medicines for heart rhythm or blood pressure
  7. St. John's wort, Hypericum perforatum
  8. sumatriptan

Sources

http://www.health-center.com/db/PageReq?SessionID=3179&TopicID=377&PageID=1459&Action=view

http://www.rxlist.com/scripts/patient/piumore.pl?mononum=857&dc_category=&order=0&type=&item=

http://www.fairlite.com/ocd/medications/effexor.shtml

http://www.psyweb.com/Drughtm/venlaf.html

 
   
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