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Dextroamphetamine
Sulfate
Brand Names: Dexedrine, Dextrostat
Overview
Dexedrine
is a stimulant and is a type of amphetamine. It is most commonly
prescribed for ADHD in children and teenagers.
Why
is this drug prescribed?
Dexedrine
is used primarily to treat Attention Deficit Disorder with
Hyperactivity. It is prescribed for the following symptoms:
- inability
to pay attention (e.g. to class work)
- hyperactivity
- impulsiveness
- disruptive
behavior
- peer
relationship problems
- unstable
mood / mood swings
Dexedrine
is also occasionally used in adults to treat narcolepsy
and, less frequently, as a short-term weight loss drug.
Warnings
and Precautions
Dexedrine
and other stimulants have the potential to be abused.
Long
term Dexedrine treatment in children may cause unwanted
effects on behavior and growth.
For
Nursing Mothers: Animal studies have shown that amphetamines
may increase the chance of birth defects if taken during
the early months of pregnancy. Amphetamines pass into breast
milk. Dexedrine has not been reported to cause problems
in nursing babies, but it is best not to breast-feed while
taking an amphetamine
Contraindications
Medical
problems which affect an individuals ability to safely
take Dexedrine are:
- an
allergic reaction to amphetamine, dextroamphetamine, ephedrine,
epinephrine, isoproterenol, metaproterenol, methamphetamine,
norepinephrine, phenylephrine, phenylpropanolamine, pseudoephedrine,
or terbutaline.
- anxiety
or severe tension
- a
history of drug abuse
- glaucoma
- heart
or blood vessel disease
- high
blood pressure or
- severe
mental illness, especially in children
- overactive
thyroid
- tourette's
syndrome or other ticsDexedrine and other amphetamines
may make the condition worse
Adverse
Reactions
- agitation/irritability
- insomnia
- dry
mouth
- headache
- nausea
- weight
loss
- hallucinations
- liver
irritation/toxicity
- increased
heart rate
- tics
- Tourette's
syndrome
- sexual
difficulties (impotence, changes in libido)
Interactions
with Drugs and Other Substances
Drugs
or substances that may interact with Dexedrine are:
- MAO
Inhibitors (within 14 days) - serious, even fatal, interactions
can occur
- Acidifying
agents like guanethidine, reserpine, and fruit juices
can lower absorption of Dexedrine.
- Alkalinizing
agents such as Diamox (acetazolamide) increase absorption
of Dexedrine and other amphetamines.
- Tricyclic
antidepressants may increase their levels when taken with
Dexedrine. Although tricyclic antidepressants may be used
with amphetamines to help make them work better, using
the two medicines together may increase the chance of
fast or irregular heartbeat, severe high blood pressure,
or high fever.
- Thorazine
(chlorpromazine), lithium, and Haldol (haloperidol) can
lower the effectiveness of Dexedrine.
- Dexedrine
increases the effects of norepinephrine.
- Amantadine
(Symmetrel), Caffeine (NoDoz), Chlophedianol (Ulone),
Methylphenidate (Ritalin), Nabilone (Cesamet), Pemoline
(Cylert) these medicines may increase the stimulant
effects of Dexedrine and cause nervousness, irritability,
trouble sleeping, and possibly convulsions (seizures).
- Appetite
suppressants (diet pills), Medicine for asthma or other
breathing problems, Medicine for colds, sinus problems,
or hay fever or other allergies (including nose drops
or sprays) - these medicines may increase the stimulant
effects of amphetamines and cause nervousness, irritability,
trouble sleeping, or convulsions (seizures), and affect
the heart and blood vessels.
- Beta-adrenergic
blocking agents (beta blockers) may increase the chance
of high blood pressure and heart problems when taken with
Dexedrine
- Digitalis
glycosides (heart medicine). Amphetamines may cause additive
effects, resulting in irregular heartbeat.
- Meperidine
when Dexedrine is taken at with meperidine, it
increases the chances of certain side effects such as
fever, convulsions, and even coma.
- Thyroid
hormonesThe effects either of these hormones or
of Dexedrine may increase when both are being taken.
Sources
1. health-center.com
http://www.health-center.com/db/PageReq?SessionID=1587&TopicID=406&PageID=2148&
Action=view
2. healthtouch.com
http://www.healthtouch.com/bin/EContent_HT/showUSPLfts.asp?fname=use0025.htm&
title=Dexedrine&cid=HT#GXX02
3. http://www.helpforadd.com/medtreat.htm
4. rxlist.com
http://www.rxlist.com/scripts/patient/piumore.pl?mononum=331&dc_category=Lose_Weight&
order=0&type=&item=
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